Environmental or self-antigens and homotypic interactions result in BCR and Toll-like receptor (TLR) signaling, amplifying the response of CLL cells to other alerts from the microenvironment and growing the activation of anti-apoptotic and proliferation pathways.31,32 Genomic scientific tests have discovered recurrent mutations in genes regulating tumor mobile-microenvironment interac... https://aeschylush207ait5.theblogfairy.com/profile