These results elevate some questions about the regulation of caspase activation. Why are two cleavage activities required to get rid of the prodomain? Our data exhibit which the cleavage at D9 is necessary for cleavage at D28. One feasible explanation is the fact that recognition and binding from the D9 https://tanshinone-i68012.p2blogs.com/27717095/the-2-minute-rule-for-tanshinone-i