E., a number of copies with the gene for cytochrome P450 isoenzyme CYP2D6 or significant morphine concentrations). These young children could be specifically sensitive for the respiratory depressant effects of codeine which has been speedily metabolized to morphine. Codeine is contraindicated for write-up-operative pain administration in these sufferers (see WARNINGS https://reidwouhy.blogunteer.com/26940755/codeine-pills-an-overview